Real-World Plasma Thymidine Kinase Activity in High-Risk and Metastatic Hormone Receptor–Positive, Human Epidermal Growth Factor Receptor 2–Negative Breast Cancer Treated With Cyclin-Dependent Kinase ...

In recent years, messenger RNA (mRNA) has emerged as a promising avenue for accurate and potent therapeutic interventions. Unlike DNA drugs, mRNA can express genetic information without the risk of ...

Long cast as a simple link between DNA and protein, messenger RNA has never offered much intrigue. But new research at The Rockefeller University suggests the molecule is up to something unexpected.

The mRNA therapeutics industry faces a critical manufacturing challenge that threatens both product safety and commercial viability. Double-stranded RNA (dsRNA) formation during in vitro transcription ...

Codon optimization is a central strategy in recombinant protein production, enabling genes from one organism to be efficiently expressed in another. Conventional methods typically replace ...

mRNA molecule, illustration. [Kateryna Kon/Science Photo Library/Getty Images] Messenger RNA (mRNA) has already transformed medicine, most notably through COVID‑19 vaccines that taught cells to act as ...

A research team from The University of Osaka and the Institute of Science Tokyo has developed a class of mRNA medicines that can sense changes in the body and autonomously adjust their therapeutic ...