DNAは二重らせん構造を持つことが知られていますが、結び目をもつかのような「i-motif」と呼ばれる特殊な構造があることも知られています。人の生きた細胞内でi-motifが初めて見つかったと報告されています。 BREAKING: Scientists have confirmed a new DNA structure inside ...

A study in the Chinese Journal of Natural Medicines reports the first high-resolution structure of the major G-quadruplex in the TMPRSS2 promoter and shows how berberine binds and stabilizes it, ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

What is it, biologically, that makes me 'me'? The biggest reason is our unique genes, our so-called 'DNA.' DNA is known to form a 'double helix' structure, where two strands are paired and twisted.

The genome is more than a linear code; it is a dynamic structure whose three-dimensional folding dictates how genes are regulated. Traditional sequencing technologies capture base-level variation but ...

A schematic of chromosome and DNA structure in the cell nucleus. Zooming into a cell reveals chromosomes inside the nucleus, and unwinding a chromosome reveals the DNA double helix. The 4D Nucleome ...

Fox Chase researchers use 3D genomic testing to improve lymphoma and sarcoma diagnosis and treatment by revealing tumor cell ...

They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...