The US Food and Drug Administration (FDA) has released draft guidance on how sponsors can utilize next-generation sequencing ...
Most gene-editing tools are blind to context. Point them at a DNA sequence and they cut, whether that sequence sits inside a ...
Scientists from Skoltech and the University of Potsdam have developed a physical theory that sheds light on how molecular ...
Scientists manufacture many biotherapeutic products in immortalized cell lines, most commonly HEK293. Residual HEK293 DNA in biotherapeutic candidates can harbor tumorigenic or retroviral sequences ...
The COVID-19 pandemic thrust messenger RNA (mRNA) into the spotlight, underscoring its promise as a nimble, programmable platform for delivering genetic instructions directly to cells. The success of ...
For stem cells to differentiate into the appropriate cell-type, transcription factors (TFs) must be tailored to highly specific expression patterns of lineage-specific genes. Abnormalities in the ...
Detecting whether osteosarcoma, a rare but aggressive bone cancer that most often affects children and adolescents, has ...
DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...